Come enjoy Jacob's presentation, free food + drinks and awesome company of fellow BMEers!
Dec 11th (Friday) 5pm at Clark 110.
Title & abstract: Peptide optimization strategies: merging experimental data with bioinformatics tools to develop potent inhibitors of angiogenesis in breast cancer
The emergence of genomics, proteomics and new peptidomics has provided several advances in the data available to develop endogenous regulators of angiogenesis. Angiogeneis, or neovascularization, is the process where new vessels form from a preexisting microvasculature, and involves interactions among several cell types. Tumors require a blood supply to grow; similarly, abrogating this blood supply is an emerging paradigm to treat diseases such as breast cancer. Our laboratory recently developed a systematic bioinformatics-based methodology to identify several endogenous regulators of angiogenesis, and experimentally verified their activity in vitro and in vivo breast xenograft models. We now have begun to optimize these sequences to enhance activity, and show different experimental techniques combined with bioinformatics tools to increase activity of endogenous therapeutics.
What is the Friday Student Seminar and Happy Hour?
FSSHH is a regularly scheduled seminar series for Johns Hopkins BME grad students and other interested students that includes a seminar talk, happy hour refreshments (beer, soda appetizers), and fun social interactions.
Why have it?
It has gives students opportunities to present their work and learn about their peers research in a relaxed environment. It also is a great opportunity for students to socialize and meet students from other labs and years.
When is it?
One or two Fridays a month @ 5pm
Where is it?
Either Homewood Clark 110, or 7th floor Library in Traylor (Talbot) at the Med Campus
What will go on?
Generally, the first 15 - 30 minutes will be spent drinking, eating snacks, etc, and the last 20-30 minutes there will be a talk by a fellow grad student. The nature of the talk is completely up to the presenter, but the hope is that they wont be overly technical, so that anybody from our very diverse department could listen and be interested and at least somewhat understand.
Questions/Comments? email lukejohnson07 AT gmail.com or cho.yoonju AT jhmi.edu